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Optimized Osmometers for
Biopharmaceutical Workflows

Advanced Instruments' bioprocessing osmometers are designed to support process development and manufacturing, ensuring biopharmaceutical products meet predetermined yield, purity, and quality standards. With the precision of freezing point technology, these instruments integrate seamlessly into any workflow, from early-stage development to GMP manufacturing.

Why choose Advanced Instruments Osmometers?

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Trusted & Reliable

65+ years of expertise delivering superior performance across diverse samples, osmolalities, and applications.

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Data Integrity & Compliance

Designed to meet 21 CFR Part 11 and EU Annex 11 requirements, ensuring regulatory compliance.

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Scalable & Workflow-Ready

Solutions optimized for every stage of bioprocessing, from research to full-scale production.
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Comprehensive Service & Support

Installation, validation, training, and maintenance services to keep your lab running efficiently.

Find the right Advanced Instruments Osmometer for your needs

All models support Pharmacopeia testing guidelines.

OsmoTECH XT Single-Sample Osmometer

OsmoTECH® XT Single-Sample Osmometer

  • Ideal for high-concentration solutions, including sugars and proteins
  • Wide operating range (0 – 4,000 mOsm/kg H2O)
  • Small sample volume requirement (20 µL)

OsmoTECH PRO Multi-Sample Micro Osmometer

OsmoTECH® PRO Multi-Sample Micro-Osmometer

  • Batch processing for higher throughput (up to 20 samples at a time)
  • Automated cleaning between samples
  • Integrated barcode scanner for sample tracking

OsmoTECH-HT-Automated-Micro-Osmometer

OsmoTECH® HT Automated Micro-Osmometer

  • High-throughput solution with 96-well plate compatibility
  • Automated operation for walk-away convenience
  • Supports network connectivity and remote monitoring

Clinical Calibrators and Controls

Bioprocess Calibrators and Controls

  • Ensures accuracy and reproducibility in biopharmaceutical testing
  • Comprehensive range for process validation and monitoring
  • Fully compliant with industry regulatory standards
  • Routinely used kits, calibrators, and controls are kept in stock

How to choose the right Bioprocessing Osmometer

Selecting the right osmometer is simple once you consider factors like sample volume and automation needs. All Advanced Instruments Osmometers use Freezing Point Technology, the "Gold Standard" for osmolality determination.

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How osmolality testing supports bioprocessing

Routine osmolality testing in biopharmaceutical labs provides confidence in process consistency, helping maintain control over titer, yield, quality, and purity. Learn more about biotech applications of osmolality.

Speak to a Specialist

Not sure which osmometer fits your needs?
Book a meeting with our Sales Specialist or fill out our form to get expert guidance.